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Question

I have very high urine calcium, 455 then 433 mg/24 hr. Serum calcium level of 10.3 mg/dl and PTH 44 pg/ml. I'm 58 years old. Little bump by jugular vein. Pressure at times behind my thyroid. Do you think it’s primary hyperparathyroidism?


Answer
Deva Boone
Answer authored by Deva Boone
Deva Boone, MD is the founder of the Southwest Parathyroid Center. As one of the most experienced parathyroid surgeons in the U.S., she has treated thousands of patients with parathyroid conditions.

We diagnose primary hyperparathyroidism with serum (blood) calcium and PTH levels. Based on those, it looks like you have primary hyperparathyroidism. A calcium of 10.3 mg/dl is too high for adults over about 40 years old. A high calcium, combined with a non-suppressed PTH, indicates primary hyperparathyroidism.

A high urine calcium (also called hypercalciuria) is not necessary for the diagnosis, but is often seen with primary hyperparathyroidism, as your kidneys have to filter the excess calcium in your blood. This will put you at risk for kidney stones and kidney damage if left untreated.

The “bump” by your jugular vein is likely unrelated. You can’t see or feel parathyroid tumors from the outside of the neck. Sometimes you can feel them inside when you swallow, as the parathyroid tumor can be right next to the esophagus. The pressure behind the thyroid may or may not be from the parathyroid tumor. In most cases, the parathyroid tumor cannot be felt at all, even if it is very large.

The only cure for primary hyperparathyroidism is parathyroid surgery. Once treated, your blood and urine calcium levels should go back to normal.

primary hyperparathyroidism Hypercalcemia Urine calcium
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